Metabolic
Retatrutide (Reta)
Clinical trials
4.80 reviewsPrimary purposes
Fat loss, Blood sugar control, Appetite regulation
Relevant conditions
Obesity, Type 2 diabetes, Fatty liver
Mechanism of action
Triple agonist of GLP-1, GIP and glucagon receptors, increasing energy expenditure and reducing appetite.
Details
In phase 2 trials retatrutide produced average weight loss of up to ~24% at 48 weeks. Phase 3 trials (TRIUMPH) are ongoing. Not yet approved.
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